Description

2-Chloro-4-(4-Methoxyphenyl)Pyrimidine is a high-purity, functionalized pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Chloro-4-(4-Methoxyphenyl)Pyrimidine
CAS No.	75634-04-7
Molecular Formula	C11H9ClN2O
Molecular Weight	220.65 g/mol
Synonyms	4-(4-Methoxyphenyl)-2-chloropyrimidine; 2-Chloro-4-(p-methoxyphenyl)pyrimidine; 2-Chloro-4-(4'-methoxyphenyl)pyrimidine; 2-Chloro-4-(4-methoxyphenyl)-pyrimidine; 4-(4-Methoxyphenyl)-2-chloro-pyrimidine; 75634-04-7; 2-Chloro-4-(4-methoxyphenyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(4-Methoxyphenyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.