Description

Benzoyl-L-Phenylalanyl-L-Valyl-L-Arginine-L-Methyl Ester CAS NO 75567-54-3 is a synthetic tetrapeptide derivative, specifically a benzoylated peptide methyl ester. This compound is a crucial advanced pharmaceutical intermediate and a valuable research-grade biochemical used in the development of novel therapeutic agents and diagnostic tools. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on peptide chemistry, enzyme inhibition studies, and drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or inhibitor in enzymatic assays to study protease activity and kinetics, particularly relevant to cardiovascular and inflammatory pathways.
• Drug Discovery & Development: Employed in high-throughput screening (HTS) and structure-activity relationship (SAR) studies to identify and optimize new therapeutic candidates.
• Reference Standard: Acts as a certified reference material (CRM) for analytical method development, validation, and quality control in peptide analysis.
• Academic Research: Utilized in university and institutional labs for investigating peptide synthesis methodologies, stability, and bio-conjugation techniques.

Basic Information

Product Name	Benzoyl-L-Phenylalanyl-L-Valyl-L-Arginine-L-Methyl Ester
CAS No.	75567-54-3
Molecular Formula	C33H47N7O6
Molecular Weight	637.78 g/mol
Synonyms	Bz-Phe-Val-Arg-OMe; Benzoyl-Phe-Val-Arg-Methyl Ester; Bz-F-V-R-OMe; Nα-Benzoyl-L-phenylalanyl-L-valyl-L-arginine methyl ester; L-Phenylalanyl-L-valyl-N6-(diaminomethylene)-L-ornithine, N2-benzoyl-, methyl ester; Thrombin Inhibitor I (Benzamidine-based); Benzamidine-derived peptide inhibitor
EINECS	Contact for details

Quality Control

Our Benzoyl-L-Phenylalanyl-L-Valyl-L-Arginine-L-Methyl Ester is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. We provide full traceability and Certificates of Analysis (COA) are available for every shipment. Production can be aligned with cGMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.