Description

5-(Aminosulphonyl)-2-Methoxy-n-[(1-Methyl-2-Pyrrolidinyl)Methyl]Benzamide Monohydrochloride is a high-purity pharmaceutical intermediate and active ingredient salt, critical for ensuring the efficacy and stability of final drug formulations. This compound is valued for its role in the synthesis of advanced therapeutic agents, particularly in the central nervous system (CNS) and metabolic disorder domains. It is primarily sought by pharmaceutical manufacturers and advanced research institutions engaged in new chemical entity (NCE) development and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel therapeutic compounds targeting specific receptors.
• Active Pharmaceutical Ingredient (API) Development: Used in the research and scale-up of new drug candidates, particularly for neurological applications.
• Process Chemistry & Optimization: Serves as a critical starting material or intermediate in route scouting and manufacturing process development.
• Reference Standard: High-purity grade suitable for use as an analytical standard in quality control (QC) and research laboratories.
• Preclinical & Clinical Research: Supplied to biotech and pharmaceutical companies for pharmacological studies and early-stage trials.
• Chemical Synthesis Research: Utilized in academic and industrial R&D for exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	5-(Aminosulphonyl)-2-Methoxy-n-[(1-Methyl-2-Pyrrolidinyl)Methyl]Benzamide Monohydrochloride
CAS No.	75514-28-2
Molecular Formula	C15H24N4O4S • HCl
Molecular Weight	400.90 g/mol (for free base: 364.44 g/mol)
Synonyms	5-(Aminosulfonyl)-2-methoxy-N-[(1-methyl-2-pyrrolidinyl)methyl]benzamide hydrochloride; 2-Methoxy-5-sulfamoyl-N-[(1-methylpyrrolidin-2-yl)methyl]benzamide hydrochloride; Amisulpride Related Compound; Benzamide, 5-(aminosulfonyl)-2-methoxy-N-[(1-methyl-2-pyrrolidinyl)methyl]-, monohydrochloride; Amisulpride Impurity; CAS 75514-28-2
EINECS	Contact for details

Quality Control

Our 5-(Aminosulphonyl)-2-Methoxy-n-[(1-Methyl-2-Pyrrolidinyl)Methyl]Benzamide Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with stringent specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support development and commercial projects requiring ICH stability data and can supply material suitable for use under cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.