Description

Oxytocin, Trp(8)- CAS NO 75511-62-5 is a synthetic analogue of the neuropeptide hormone oxytocin, specifically modified at the 8th position with a tryptophan residue. This modification is designed to enhance receptor binding affinity and metabolic stability, making it a critical tool for advanced biochemical and pharmacological research. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on neuroendocrinology, peptide therapeutics, and behavioral studies.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies investigating oxytocin receptor (OXTR) signaling, function, and modulation.
• Drug Discovery & Development: Serves as a lead compound or biochemical tool for developing novel therapeutics targeting social behavior, stress, and reproductive functions.
• Neuroscience Studies: Applied in vitro and in vivo to explore the role of oxytocin pathways in social bonding, anxiety, and maternal behavior.
• Biochemical Assays: Employed in receptor binding assays, functional cellular assays (e.g., calcium flux), and signal transduction studies to characterize peptide-receptor interactions.
• Peptide Chemistry Reference: Acts as a model compound for studying structure-activity relationships (SAR) in peptide hormone analogues.
• Veterinary Research: Investigated for potential applications in animal reproductive health and behavioral management.

Basic Information

Product Name	Oxytocin, Trp(8)- CAS NO 75511-62-5
CAS No.	75511-62-5
Molecular Formula	C₄₆H₆₆N₁₂O₁₂S₂
Molecular Weight	1051.2 g/mol
Synonyms	8-Tryptophan-oxytocin; [8-Trp]-Oxytocin; Oxytocin, 8-tryptophan-; Tocinoic Acid, 8-tryptophan-; 8-Trp-OXT; L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-tryptophyl-L-glycinamide (1-6)-disulfide; [Mpa¹, Tyr², Ile³, Gln⁴, Asn⁵, Cys⁶, Pro⁷, Trp⁸, Gly⁹]-Oxytocin; Oxytocin Tryptophan-8 Analogue
EINECS	Contact for details

Quality Control

Our Oxytocin, Trp(8)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade standards. Specifications are designed to meet the rigorous demands of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by AAA)
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.