Description

Z-Gly-Gly-Met-Oh CAS NO 75501-70-1 is a protected tetrapeptide derivative, specifically the Cbz (Z)-protected precursor to the Gly-Gly-Met sequence. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled assembly of complex peptides and proteins. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors developing therapeutic peptides, biochemical tools, and advanced biomaterials.

Application

• Pharmaceutical Intermediate: Key raw material for the synthesis of therapeutic peptides targeting various metabolic and signaling pathways.
• Biochemical Research: Used as a standard or reagent in enzymatic studies, substrate specificity assays, and proteomics research.
• Peptide Library Construction: Essential building block for creating combinatorial peptide libraries for drug discovery and screening.
• Conjugate Vaccine Development: Serves as a carrier peptide or linker in the design of synthetic conjugate vaccines.
• Cell Culture & Media Supplement: Potential component in specialized cell culture media formulations for specific cellular studies.
• Enzyme Inhibitor Synthesis: Precursor for developing peptide-based inhibitors of proteases and other enzymes.

Basic Information

Product Name	Z-Gly-Gly-Met-Oh
CAS No.	75501-70-1
Molecular Formula	C17H23N3O6S
Molecular Weight	397.45 g/mol
Synonyms	N-Carbobenzoxy-glycyl-glycyl-L-methionine; Z-Gly-Gly-L-Met-OH; Cbz-Gly-Gly-Met-OH; Nα-Cbz-Gly-Gly-L-Methionine; Benzyloxycarbonyl-glycyl-glycyl-L-methionine; (2S)-2-[[2-[(2-[[(Benzyloxy)carbonyl]amino]acetyl)amino]acetyl]amino]-4-(methylsulfanyl)butanoic acid; Glycyl-glycyl-L-methionine N-Cbz derivative; CBZ-Gly-Gly-Met
EINECS	Contact for details

Quality Control

Our Z-Gly-Gly-Met-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR). Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research and cGMP-grade manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.