Description

2-Cyclopropyl-5-Nitropyrimidine-4,6-Diol is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the nitropyrimidine scaffold is a privileged structure. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the biological activity of the nitropyrimidine core.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex heterocyclic compounds in custom synthesis and process development.
• Material Science Research: Potential use in the synthesis of organic electronic materials or metal-organic frameworks (MOFs) due to its functionalized aromatic system.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and discovery chemistry.

Basic Information

Product Name	2-Cyclopropyl-5-Nitropyrimidine-4,6-Diol
CAS No.	75438-77-6
Molecular Formula	C7H7N3O4
Molecular Weight	197.15 g/mol
Synonyms	5-Nitro-2-cyclopropyl-4,6-pyrimidinediol; 2-Cyclopropyl-5-nitropyrimidine-4,6(1H,5H)-dione; 4,6-Dihydroxy-2-cyclopropyl-5-nitropyrimidine; 5-Nitro-2-cyclopropylpyrimidine-4,6-diol; 2-Cyclopropyl-5-nitro-1H,3H-pyrimidine-4,6-dione; 75438-77-6; 2-Cyclopropyl-5-nitropyrimidine-4,6-dione
EINECS	Contact for details

Quality Control

Our 2-Cyclopropyl-5-Nitropyrimidine-4,6-Diol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.