Description

Lysine(Butyryl)-Oh CAS NO 75396-30-4 is a modified amino acid derivative where the ε-amino group of lysine is acylated with a butyryl moiety. This specific chemical modification is crucial for advanced biochemical research and pharmaceutical development, particularly in the study of protein post-translational modifications and enzyme activity. It serves as a key building block and research tool for scientists and manufacturers in the life sciences sector. Target industries include pharmaceutical R&D, biotechnology, and academic research institutions focused on proteomics and metabolic studies.

Application

• Pharmaceutical Intermediate: Used in the research and synthesis of novel drug candidates, particularly those targeting metabolic pathways or requiring specific acylated amino acid motifs.
• Biochemical Research: Serves as a critical reagent and standard in studying lysine acylation, a key post-translational modification involved in gene regulation and cellular signaling.
• Peptide Synthesis: Acts as a protected or modified lysine derivative in solid-phase and solution-phase peptide synthesis for creating custom peptides with specific properties.
• Enzyme Substrate/Inhibitor Studies: Utilized to investigate the activity and specificity of enzymes like sirtuins and histone deacetylases (HDACs) that are involved in deacylation reactions.
• Proteomics & Biomarker Discovery: Employed in mass spectrometry-based proteomic workflows as a reference compound for identifying and quantifying acylated peptides in complex biological samples.
• Nutritional Science Research: Used in metabolic studies to understand the fate and function of modified amino acids in biological systems.

Basic Information

Product Name	Lysine(Butyryl)-Oh
CAS No.	75396-30-4
Molecular Formula	C10H20N2O3
Molecular Weight	216.28 g/mol
Synonyms	N6-Butyryl-L-lysine; Nε-Butyryl-L-lysine; N6-Butyryllysine; L-Lysine, N6-butanoyl-; Butyryl-lysine; K(Bu); N-Butyryl-L-lysine; Nε-Butanoyl-L-lysine
EINECS	Contact for details

Quality Control

Our Lysine(Butyryl)-Oh is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation. A Certificate of Analysis (COA) detailing specific results for identity, purity, and related substances is provided with every shipment. We adhere to relevant quality guidelines suitable for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent product degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.