Description

Cyclo(Glycine-Histidyl-Glycyl-Histidyl-Glycyl-Histidyl-Glycyl) is a synthetic cyclic peptide composed of repeating glycine and histidine residues. This compound is significant for its role as a model system in biochemical research, particularly for studying metal ion coordination and peptide folding dynamics. It is primarily needed by research institutions and pharmaceutical companies engaged in advanced peptide chemistry, enzymology, and the development of novel diagnostic or therapeutic agents.

Application

• Biochemical Research: Used as a model peptide to study zinc-binding motifs and histidine-rich peptide structures.
• Enzyme Mimicry Studies: Serves as a scaffold for investigating catalytic activity in metalloenzymes.
• Pharmaceutical Development: Potential intermediate or reference standard in the discovery of peptide-based therapeutics.
• Coordination Chemistry: Acts as a ligand for complexation studies with transition metals like copper, nickel, and zinc.
• Material Science: Investigated for creating bio-inspired materials and nanostructures through self-assembly.
• Diagnostic Reagent Formulation: May be utilized in developing sensitive assays that rely on metal-peptide interactions.

Basic Information

Product Name	Cyclo(Glycine-Histidyl-Glycyl-Histidyl-Glycyl-Histidyl-Glycyl)
CAS No.	75356-90-0
Molecular Formula	C30H40N18O9
Molecular Weight	748.75 g/mol
Synonyms	Cyclo(Gly-His-Gly-His-Gly-His-Gly); Cyclic (Gly-His-Gly-His-Gly-His-Gly); c(GHGHGHG); Histidine-Glycine Cyclic Heptapeptide; Cyclo(Gly-His-Gly-His-Gly-His-Gly) Peptide; CAS 75356-90-0; Cyclic Heptapeptide GHGHGHG
EINECS	Contact for details

Quality Control

Our Cyclo(Glycine-Histidyl-Glycyl-Histidyl-Glycyl-Histidyl-Glycyl) is produced under stringent conditions to ensure high purity and batch-to-batch consistency. Quality is verified through comprehensive analytical techniques including HPLC, MS, and NMR. A Certificate of Analysis (COA) detailing purity, identity, and specific impurities is provided with each batch to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed in a dry environment to prevent moisture absorption. For long-term stability, consider storage under inert atmosphere or at lower temperatures (2-8°C).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.