Description

n-(Epsilon29),n-(Epsilon59)-Bis(Methylsulfonylethoxycarbonyl)Proinsulin is a chemically modified derivative of proinsulin, a key precursor in insulin biosynthesis. This compound is of significant value in pharmaceutical research and development, particularly for studying insulin processing, stability, and structure-activity relationships. It serves as a critical intermediate and analytical standard for researchers and manufacturers in the biopharmaceutical sector focused on diabetes therapeutics and peptide chemistry.

Application

• Pharmaceutical Research Intermediate: Used as a key synthetic precursor in the development and study of novel insulin analogs and delivery systems.
• Biochemical Standard: Serves as a high-purity reference standard for analytical methods such as HPLC and mass spectrometry in quality control laboratories.
• Peptide Chemistry Studies: Employed in academic and industrial research to investigate peptide protection strategies, folding, and enzymatic conversion processes.
• Process Development: Utilized in the scale-up and optimization of insulin manufacturing processes within biopharmaceutical production.
• Stability and Formulation Research: Aids in studies aimed at improving the shelf-life and efficacy of insulin-based pharmaceutical formulations.

Basic Information

Product Name	n-(Epsilon29),n-(Epsilon59)-Bis(Methylsulfonylethoxycarbonyl)Proinsulin
CAS No.	75301-50-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Bis-Msc-Proinsulin; Nε29,Nε59-Bis(2-((Methylsulfonyl)ethoxy)carbonyl)proinsulin; Proinsulin, N-(29-lysine), N'-(59-lysine)-bis[N-[2-[(methylsulfonyl)ethoxy]carbonyl]]-; Msc-Proinsulin derivative; Lys29,Lys59-bis(Msc)-Proinsulin; Protected Proinsulin Derivative; Insulin Precursor Derivative
EINECS	Contact for details

Quality Control

Our n-(Epsilon29),n-(Epsilon59)-Bis(Methylsulfonylethoxycarbonyl)Proinsulin is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) detailing purity, identity, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature or as specified on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.