Description

N(Alpha)-ε-Acetylglucagon is a chemically modified derivative of the peptide hormone glucagon, designed for enhanced stability and specific research applications. This high-purity compound is critical for advancing studies in endocrinology, metabolic disease research, and peptide chemistry. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing novel therapeutic agents and diagnostic tools.

Application

• Biochemical Research: Used as a stable analog in studies investigating glucagon receptor binding, signal transduction pathways, and hormone metabolism.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the research and development of new diabetes and metabolic disorder therapeutics.
• Analytical Standard: Employed as a high-purity calibrant in HPLC, LC-MS, and other analytical methods for quantifying glucagon and its derivatives.
• Peptide Chemistry Studies: Utilized in academic and industrial labs to study the effects of acetylation on peptide stability, solubility, and biological activity.
• Diagnostic Reagent Manufacturing: Acts as a critical component in the development of immunoassays and diagnostic kits for measuring glucagon levels.

Basic Information

Product Name	N(Alpha)-ε-Acetylglucagon
CAS No.	75240-88-9
Molecular Formula	C153H225N43O49S
Molecular Weight	~3483.8 g/mol
Synonyms	Acetylglucagon; Glucagon, N(alpha)-acetyl-, ε-acetyl-; Nα-Acetyl-ε-acetylglucagon; Monoacetylglucagon; Glucagon acetylated derivative; 75240-88-9; Glucagon (acetylated)
EINECS	Contact for details

Quality Control

Our N(Alpha)-ε-Acetylglucagon is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide comprehensive Certificates of Analysis (COA) detailing all specifications, ensuring traceability and compliance with research-grade standards. Our quality commitment supports reliable and reproducible results for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant or under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in dilute acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.