Description

Pyrimidine, 2-Chloro-5-(4-Fluorophenyl)- is a high-purity halogenated pyrimidine derivative, a crucial building block in advanced organic synthesis. Its core value lies in its versatile reactivity, enabling the construction of complex molecular architectures for research and development. This intermediate is primarily needed by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Material Science Research: Serves as a precursor for the synthesis of specialized organic electronic materials and liquid crystals.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Pyrimidine, 2-Chloro-5-(4-Fluorophenyl)-
CAS No.	75175-39-2
Molecular Formula	C10H6ClFN2
Molecular Weight	208.62 g/mol
Synonyms	2-Chloro-5-(4-fluorophenyl)pyrimidine; 5-(4-Fluorophenyl)-2-chloropyrimidine; 2-Chloro-5-(p-fluorophenyl)pyrimidine; 4-Fluorophenyl-2-chloropyrimidine; 2-Chloro-5-(4'-fluorophenyl)pyrimidine; (4-Fluorophenyl)-2-chloropyrimidine; 75175-39-2; 2-Chloro-5-(4-fluorophenyl)pyrimidine (CAS 75175-39-2)
EINECS	Contact for details

Quality Control

Our Pyrimidine, 2-Chloro-5-(4-Fluorophenyl)- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all critical specifications. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.