Description

1,8-Naphthyridine-3-Carboxylic Acid, 1,4-Dihydro-1-Ethenyl-6-Fluoro-4- Oxo-7-(1-Piperazinyl)-,Monohydrochloride is a high-purity pharmaceutical intermediate of significant commercial importance. This compound is valued for its role as a key building block in the synthesis of advanced active pharmaceutical ingredients (APIs), particularly within the fluoroquinolone antibiotic class. It is essential for manufacturers and research institutions engaged in the development and production of novel antibacterial agents, serving a critical function in the pharmaceutical supply chain.

Application

• Pharmaceutical Intermediate: Primary use as a critical precursor in the synthesis of fluoroquinolone antibiotics.
• Active Pharmaceutical Ingredient (API) Development: Serves as a key structural component in research and development of new antibacterial drugs.
• Chemical Synthesis Research: Used in academic and industrial laboratories for studying structure-activity relationships in medicinal chemistry.
• Process Chemistry: Employed in scale-up and optimization of manufacturing routes for complex pharmaceutical molecules.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and regulatory testing.

Basic Information

Item	Details
Product Name	1,8-Naphthyridine-3-Carboxylic Acid, 1,4-Dihydro-1-Ethenyl-6-Fluoro-4- Oxo-7-(1-Piperazinyl)-,Monohydrochloride
CAS No.	75167-16-7
Molecular Formula	C17H19FN4O3 • HCl
Molecular Weight	382.82 g/mol
Synonyms	1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid hydrochloride; 1-Ethyl-6-fluoro-7-(piperazin-1-yl)-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid hydrochloride; Enoxacin Hydrochloride; Enoxacin HCl; AT-2266 Hydrochloride; CI-919 Hydrochloride; Flumark Hydrochloride; Gyramid Hydrochloride
EINECS	Contact for details

Quality Control

Our 1,8-Naphthyridine-3-Carboxylic Acid, 1,4-Dihydro-1-Ethenyl-6-Fluoro-4- Oxo-7-(1-Piperazinyl)-,Monohydrochloride is manufactured under strict quality management systems. The product undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each batch and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.