Description

Tyr-Gly-Gly-Phe-Leu-Arg-Lys-Arg CAS NO 75106-72-8 is a synthetic heptapeptide sequence, also known as a fragment of the dynorphin A family, with significant research and development applications. This compound is valued for its role in studying opioid receptor interactions and neurobiological pathways. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on neuroscience, peptide therapeutics, and biochemical analysis.

Application

• Neuroscience Research: Used as a reference standard or active agent in studies investigating κ-opioid receptor (KOR) signaling, pain modulation, and addiction pathways.
• Biochemical Assay Development: Serves as a critical component in the development and validation of immunoassays (ELISA, RIA) and receptor binding assays.
• Pharmaceutical R&D: Acts as a key intermediate or pharmacophore model in the discovery and design of novel peptide-based neurotherapeutics.
• Academic Studies: Employed in university and institutional labs for teaching and advanced research on peptide chemistry and neuropeptide function.
• Quality Control Reference: Provides a high-purity standard for the quality control and analysis of related peptide substances in manufacturing.

Basic Information

Product Name	Tyr-Gly-Gly-Phe-Leu-Arg-Lys-Arg
CAS No.	75106-72-8
Molecular Formula	C44H71N15O10
Molecular Weight	946.1 g/mol
Synonyms	Dynorphin A (1-7); Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Lys (common alternate); H-Tyr-Gly-Gly-Phe-Leu-Arg-Lys-Arg-OH; Dynorphin A 1-7 heptapeptide; Leu-Enkephalin, Arg6, Lys7, Arg8-; [Arg6, Lys7, Arg8]-Leu-Enkephalin; Peptide sequence YGGFLRKR
EINECS	Contact for details

Quality Control

Our Tyr-Gly-Gly-Phe-Leu-Arg-Lys-Arg is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, related substances, and residual solvents are provided to ensure compliance with research-grade standards and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and should be kept under desiccant. For long-term storage, consider under an inert atmosphere to prevent oxidation. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Conforms
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.