Description

Enkephalinamide-Met, Ala(2,3)- is a synthetic peptide analog of the endogenous opioid peptide enkephalin, specifically modified at the methionine and alanine residues. This compound is of significant interest for its potential role in neurobiological research and as a tool for studying opioid receptor interactions and signal transduction pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in neuroscience, pain management research, and peptide-based drug discovery.

Application

• Neuroscience Research: As a key biochemical tool for investigating the function and modulation of delta and mu opioid receptors in the central nervous system.
• Pharmacological Studies: Used in in vitro and in vivo assays to study analgesic pathways, receptor binding affinity, and the structure-activity relationships (SAR) of opioid peptides.
• Drug Discovery & Development: Serves as a reference standard or a lead compound in the design and screening of novel peptide-based therapeutics for pain and neurological disorders.
• Biochemical Reagent: Employed in enzymatic stability studies and as a substrate to investigate peptidase activity and peptide metabolism.
• Academic Research: A critical reagent for university laboratories conducting fundamental research on neuropeptides, neurotransmission, and behavioral pharmacology.

Basic Information

Product Name	Enkephalinamide-Met, Ala(2,3)-
CAS No.	75059-08-4
Molecular Formula	C28H38N6O7S
Molecular Weight	602.70 g/mol
Synonyms	[Met5]-Enkephalinamide; H-Tyr-Gly-Gly-Phe-Met-NH2; Methionine Enkephalin Amide; Enkephalin, methionine- (5-)-amide; L-Tyrosylglycylglycyl-L-phenylalanyl-L-methioninamide; YGGFM-NH2; Opioid Peptide YGGFM-NH2; (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenyl-N-[(2S)-1-[[(2S)-1-amino-3-methylsulfanyl-1-oxopropan-2-yl]amino]-3-methylsulfanyl-1-oxopropan-2-yl]propanamide
EINECS	Contact for details

Quality Control

Our Enkephalinamide-Met, Ala(2,3)- is produced under strict quality management protocols suitable for research applications. Each batch undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). A detailed Certificate of Analysis (COA) documenting purity, peptide content, and solvent residues is provided with every shipment to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by AAA)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.