Description

Somatostatin 28 CAS NO 75037-27-3 is a biologically active peptide hormone, a longer isoform of somatostatin, known for its potent inhibitory effects on the secretion of various hormones. This compound is critical for research and development in endocrinology and metabolic studies, providing a key tool for understanding hormonal regulation pathways. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotech companies engaged in peptide synthesis, drug discovery, and advanced biochemical assays.

Application

• Endocrine Research: Used as a reference standard and active agent in studies investigating the regulation of growth hormone, insulin, and glucagon secretion.
• Drug Discovery & Development: Serves as a lead compound or pharmacological tool for developing novel therapeutics targeting somatostatin receptors (SSTRs) for conditions like acromegaly and neuroendocrine tumors.
• Biochemical Assays: Employed in receptor binding studies, enzyme-linked immunosorbent assays (ELISAs), and other in vitro bioassays to characterize biological activity and potency.
• Academic & Clinical Research: Fundamental for university and hospital labs studying its physiological roles in the central nervous system, gastrointestinal tract, and pancreatic function.
• Peptide Synthesis & Custom Manufacturing: Used as a starting material or intermediate for the custom synthesis of peptide analogs and conjugates with modified biological properties.
• Diagnostic Development: Potential use in the development of diagnostic kits and imaging agents for detecting somatostatin receptor-expressing tissues.

Basic Information

Product Name	Somatostatin 28
CAS No.	75037-27-3
Molecular Formula	C149H226N42O41S3
Molecular Weight	3279.8 g/mol
Synonyms	Somatostatin-28; SRIF-28; Growth Hormone Release-Inhibiting Hormone (1-28); Somatotropin Release-Inhibiting Factor (1-28); H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (Disulfide bridge: Cys3-Cys14); Somatostatin 1-28; SS-28
EINECS	Contact for details

Quality Control

Our Somatostatin 28 is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 8.0%
Acetate Content (HPIC)	≤ 12.0%
Single Impurity (HPLC)	≤ 2.0%
Biological Activity	Assayed in appropriate receptor binding or functional assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.