Description

1,2,4,4A-Tetrahydro-9-Fluor-7-Phenyl-5H(1,4)Oxazino(4,3-A)(1,4)Benzodi Azepin [German] is a specialized heterocyclic organic compound featuring a complex fused-ring structure that incorporates fluorine and phenyl groups. This molecular architecture makes it a valuable advanced pharmaceutical intermediate for research and development in medicinal chemistry. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly within the benzodiazepine analog space.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel benzodiazepine-derived therapeutic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new compounds with targeted biological activity.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step synthesis of potential drug candidates for central nervous system (CNS) disorders.
• Chemical Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Academic & Institutional Research: Employed in universities and research institutes for studies in organic synthesis and heterocyclic chemistry.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	1,2,4,4A-Tetrahydro-9-Fluor-7-Phenyl-5H(1,4)Oxazino(4,3-A)(1,4)Benzodi Azepin [German]
CAS No.	75017-27-5
Molecular Formula	C19H17FN2O
Molecular Weight	308.35 g/mol
Synonyms	9-Fluoro-7-phenyl-1,2,4,4a-tetrahydro-5H-[1,4]oxazino[4,3-a][1,4]benzodiazepine; 7-Phenyl-9-fluoro-1,2,4,4a-tetrahydro-5H-[1,4]oxazino[4,3-a][1,4]benzodiazepine; 75017-27-5; 9-Fluoro-7-phenyl-1,2,4,4a-tetrahydro-5H-[1,4]oxazino[4,3-a][1,4]benzodiazepin; Fluorinated benzodiazepine oxazine derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all test results are provided with each shipment. We support development projects with material produced under GMP-like conditions for non-clinical and early-phase clinical studies, with specifications scalable to meet project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.