Description

6-Amino-3,6-dideoxy-5-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-β-L-lyxo-heptopyranosyl)-3-(methylamino)-D-myo-inositol is a structurally complex aminoglycoside derivative of significant interest in advanced pharmaceutical research. This compound matters as a sophisticated chemical intermediate for the development of novel antibiotics and other therapeutic agents targeting bacterial infections. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on synthesizing next-generation antimicrobials and exploring complex carbohydrate chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel aminoglycoside and aminocyclitol antibiotics.
• Antimicrobial Research: Used in biochemical studies to investigate mechanisms of action against resistant bacterial strains.
• Glycobiology Studies: Serves as a specialized substrate or probe for studying enzyme interactions and carbohydrate metabolism pathways.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize drug potency and reduce toxicity.
• Reference Standard: Utilized as a high-purity analytical standard for quality control in pharmaceutical manufacturing.
• Bioconjugate Development: Potential use in creating targeted drug delivery systems due to its functionalizable amino groups.

Basic Information

Item	Details
Product Name	6-Amino-3,6-dideoxy-5-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-β-L-lyxo-heptopyranosyl)-3-(methylamino)-D-myo-inositol
CAS No.	74958-28-4
Molecular Formula	C17H34N4O8
Molecular Weight	422.48 g/mol
Synonyms	6'-N-Methylgentamicin C2a; Antibiotic JI-20A; Gentamicin C2a, 6'-N-methyl-; 6'-N-Methylgentamicin; 1-N-[(S)-4-Amino-2-hydroxybutyryl]-6'-N-methylgentamicin C1a; (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-Diamino-3-[[(2R,3R,4R,5R)-5-(aminomethyl)-3,4-dihydroxyoxolan-2-yl]oxy]-2-hydroxycyclohexyl]oxy-5-methylaminooxane-3,4,5-triol; 6'-N-Methylgentamicin C1a; 4-O-(6-Amino-6-deoxy-α-D-glucopyranosyl)-1-N-[(S)-4-amino-2-hydroxybutyryl]-6'-N-methylgentamicin C1a
EINECS	Contact for details

Quality Control

Our 6-Amino-3,6-dideoxy-5-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-β-L-lyxo-heptopyranosyl)-3-(methylamino)-D-myo-inositol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent tests for residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details
Bacterial Endotoxins	< 1.0 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.