Description

4-Pyrimidinamine, 5-Ethynyl-2-Methoxy- (9Ci) is a specialized pyrimidine derivative featuring an ethynyl substituent, which serves as a versatile synthetic handle for further chemical elaboration. This compound is a valuable high-purity building block in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Material Science: Serves as a monomer or cross-linking agent in the creation of specialty polymers and advanced organic materials.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry due to its reactive ethynyl group for "click chemistry" applications.
• Academic & R&D: Utilized in research laboratories for methodological studies and the exploration of new synthetic pathways in heterocyclic chemistry.

Basic Information

Product Name	4-Pyrimidinamine, 5-Ethynyl-2-Methoxy- (9Ci)
CAS No.	74954-62-4
Molecular Formula	C7H7N3O
Molecular Weight	149.15 g/mol
Synonyms	5-Ethynyl-2-methoxypyrimidin-4-amine; 2-Methoxy-5-ethynylpyrimidin-4-amine; 4-Amino-5-ethynyl-2-methoxypyrimidine; 5-Ethynyl-2-methoxy-4-pyrimidinamine; 5-Ethynyl-2-methoxy-4-aminopyrimidine; 74954-62-4; 4-Pyrimidinamine, 5-ethynyl-2-methoxy-
EINECS	Contact for details

Quality Control

Our 4-Pyrimidinamine, 5-Ethynyl-2-Methoxy- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.