Description

Msh, 13-(4-Azido-Phe)α- is a specialized synthetic peptide derivative containing a photoreactive azido phenylalanine moiety. This compound is of significant value in biochemical research and pharmaceutical development for its utility as a photoaffinity labeling agent. It is primarily needed by researchers and manufacturers in the fields of proteomics, drug discovery, and bioconjugation chemistry, where it is used to study protein-ligand interactions and develop targeted therapeutic agents.

Application

• Photoaffinity Labeling (PAL): A critical tool for mapping binding sites and studying the interactions between proteins and small molecules or other biomolecules.
• Proteomics Research: Used to identify and characterize unknown protein targets and their functional sites.
• Drug Discovery & Development: Employed in the design and validation of novel drug candidates by creating covalent probes.
• Bioconjugation & Chemical Biology: Serves as a versatile crosslinker for attaching labels, drugs, or other functional groups to biomolecules under controlled UV light activation.
• Structural Biology Studies: Aids in elucidating three-dimensional protein structures and dynamics through covalent trapping of complexes.
• Enzyme Mechanism Analysis: Used to investigate active sites and catalytic mechanisms of enzymes.

Basic Information

Product Name	Msh, 13-(4-Azido-Phe)α-
CAS No.	74927-13-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	13-(4-Azido-L-phenylalanine)-α-MSH; α-MSH analog with 4-azido-Phe; Photoactivatable α-Melanocyte Stimulating Hormone analog; 4-Azido-Phe(13)-α-MSH; N-Acetyl-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 (4-Azido-Phe at position 13); Azido-phenylalanine modified MSH; Photoreactive MSH peptide; CAS 74927-13-2
EINECS	Contact for details

Quality Control

Our Msh, 13-(4-Azido-Phe)α- is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Quality is verified through advanced analytical techniques including HPLC, MS, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider storing under an inert atmosphere or desiccant to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.