Description

4-Amino-3-Hydroxyphenylalanine is a specialized aromatic amino acid derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its unique structure, featuring both amino and hydroxyl functional groups on the phenyl ring, makes it a valuable precursor for the development of complex bioactive molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel drug candidates, diagnostic agents, and fine chemicals, particularly those targeting neurological and metabolic pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of potential therapeutic agents, including enzyme inhibitors and receptor modulators.
• Biochemical Research: Used in the study of amino acid metabolism, enzyme mechanisms, and as a substrate or inhibitor in various biochemical assays.
• Peptide Synthesis: Serves as a modified amino acid residue for incorporating specific functional groups into synthetic peptides to alter their stability, activity, or binding properties.
• Diagnostic Agent Development: Employed in the design and synthesis of contrast agents or molecular probes for imaging techniques.
• Fine Chemical Synthesis: Acts as a building block for creating complex organic molecules with applications in material science and specialty chemistry.

Basic Information

Product Name	4-Amino-3-Hydroxyphenylalanine
CAS No.	74923-08-3
Molecular Formula	C9H12N2O3
Molecular Weight	196.20 g/mol
Synonyms	3-Hydroxy-4-aminophenylalanine; L-4-Amino-3-hydroxyphenylalanine; 2-Amino-3-(4-amino-3-hydroxyphenyl)propanoic acid; (2S)-2-Amino-3-(4-amino-3-hydroxyphenyl)propanoic acid; 4-Amino-3-hydroxy-DL-phenylalanine; 3-Hydroxy-4-amino-DL-phenylalanine; 4-Amino-3-hydroxyphenylalanine (racemic)
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Hydroxyphenylalanine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for purity and chiral integrity, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to cGMP principles where applicable to support its use in research and development for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation and clumping.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (for enantiopure grade)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.