Description

Fortimicin Ao CAS NO 74918-35-7 is a specialized aminoglycoside antibiotic compound of significant interest in pharmaceutical research and development. Its primary value lies in its potent antibacterial activity, particularly against a spectrum of Gram-negative and some Gram-positive bacteria. This makes it a critical intermediate and reference standard for the synthesis and quality control of advanced antibiotic formulations. Key industries that require this high-purity compound include pharmaceutical R&D, biotechnology, and academic research institutions focused on antimicrobial studies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel aminoglycoside antibiotics and derivatives.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control testing of antibiotic products.
• Microbiological Research: Employed in studies investigating bacterial resistance mechanisms, structure-activity relationships (SAR), and the development of new antimicrobial agents.
• Active Pharmaceutical Ingredient (API) Development: Acts as a core component in the formulation and preclinical development of new antibiotic drugs.
• Biochemical Assays: Utilized in enzymatic and receptor-based assays to study the interaction and inhibition of bacterial protein synthesis.

Basic Information

Product Name	Fortimicin Ao
CAS No.	74918-35-7
Molecular Formula	C19H37N5O8
Molecular Weight	463.53 g/mol
Synonyms	Fortimicin A; Antibiotic FR-31564; FR-31564; (2S,3R,4S,5S,6R)-5-Amino-2-[[(2S,3S,4R,5S)-5-amino-2-(aminomethyl)-3,4-dihydroxyoxolan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4-diol; 1-N-[(S)-4-Amino-2-hydroxybutyryl]-fortimicin A; Fortimicin AO
EINECS	Contact for details

Quality Control

Our Fortimicin Ao is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and stringent controls for residual solvents and impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with in-house specifications suitable for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 2.0%; Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.