Description

Argatroban is a potent, selective, and reversible direct thrombin inhibitor used as an anticoagulant. This high-purity active pharmaceutical ingredient (API) is critical for the formulation of life-saving medications that prevent and treat thrombotic disorders. It is essential for pharmaceutical manufacturers and research institutions developing injectable anticoagulant therapies, particularly for patients with heparin-induced thrombocytopenia (HIT).

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable anticoagulant drugs.
• Anticoagulation Therapy: Formulation for the prophylaxis and treatment of thrombosis in patients with HIT (Heparin-Induced Thrombocytopenia).
• Cardiovascular Procedures: Used as an anticoagulant during percutaneous coronary interventions (PCI) in at-risk patients.
• Research & Development: Critical reference standard and building block in cardiovascular and hematological research for novel anticoagulant discovery.
• Generic Drug Manufacturing: Sourcing of API for the production of generic argatroban formulations.

Basic Information

Product Name	Argatroban
CAS No.	74863-84-6
Molecular Formula	C23H36N6O5S
Molecular Weight	508.63 g/mol
Synonyms	(2R,4R)-4-Methyl-1-[N2-((RS)-3-methyl-1,2,3,4-tetrahydro-8-quinolinesulfonyl)-L-arginyl]-2-piperidinecarboxylic acid; Argipidine; MD-805; Novastan; Slonnon; 2-Piperidinecarboxylic acid, 1-[5-[(aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-, (2R,4R)-; Direct Thrombin Inhibitor
EINECS	Contact for details

Quality Control

Our Argatroban is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity pharmacopeial standards, including identification, assay, and control of specified impurities. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing results against specifications for identity, purity, and safety.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.