Description

1-Pyrrolidinecarboxamide, n-(5-(2-Fluorophenyl)-2,3-Dihydro-1-Methyl-2 -Oxo-1H-1,4-Benzodiazepin-7-Yl)- is a high-purity, specialized benzodiazepine derivative with significant importance in advanced pharmaceutical research and development. This compound serves as a critical pharmaceutical intermediate or reference standard for the synthesis and study of novel therapeutic agents targeting the central nervous system. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of active pharmaceutical ingredients (APIs) focused on neurological and psychiatric drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical manufacturing (HPLC, LC-MS).
• Drug Discovery Research: Serves as a core scaffold or precursor in medicinal chemistry programs for developing new CNS-targeting therapeutics.
• Biochemical Research: Utilized in vitro studies to investigate interactions with GABA receptors and related neurological pathways.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for potential drug candidates.
• Custom Synthesis: A starting material for the preparation of more complex, targeted molecules for preclinical evaluation.

Basic Information

Product Name	1-Pyrrolidinecarboxamide, n-(5-(2-Fluorophenyl)-2,3-Dihydro-1-Methyl-2 -Oxo-1H-1,4-Benzodiazepin-7-Yl)-
CAS No.	74858-71-2
Molecular Formula	C21H21FN4O2
Molecular Weight	380.42 g/mol
Synonyms	7-Nitro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one; 7-Nitro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; N-Desalkylflurazepam; Ro 5-3027; Norflurazepam; 1-Pyrrolidinecarboxamide, N-[5-(2-fluorophenyl)-2,3-dihydro-1-methyl-2-oxo-1H-1,4-benzodiazepin-7-yl]-; 7-Amino-N-desalkylflurazepam derivative
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidinecarboxamide derivative is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.