Description

Urea, n-(5-(2-Fluorophenyl)-2,3-Dihydro-1-Methyl-2-Oxo-1H-1,4-Benzodia Zepin-7-Yl)-N(Sup 1)-Methyl- is a specialized benzodiazepine derivative with a complex molecular structure, serving as a critical advanced intermediate in modern pharmaceutical synthesis. This compound matters for its role in the research and development of novel therapeutic agents, particularly those targeting the central nervous system. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-purity intermediate to ensure the integrity and efficacy of their final active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the discovery and optimization of new drug candidates targeting neurological pathways.
• Preclinical Studies: Serves as a reference standard or starting material for pharmacokinetic and pharmacodynamic studies.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for complex heterocyclic compounds.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized fine chemicals.
• Academic Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) of fluorinated heterocycles.

Basic Information

Product Name	Urea, n-(5-(2-Fluorophenyl)-2,3-Dihydro-1-Methyl-2-Oxo-1H-1,4-Benzodia Zepin-7-Yl)-N(Sup 1)-Methyl-
CAS No.	74858-67-6
Molecular Formula	C19H18FN3O2
Molecular Weight	339.37 g/mol
Synonyms	7-Chloro-1-methyl-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one urea derivative; N-Methyl-N'-[7-chloro-1-methyl-5-(2-fluorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]urea; A benzodiazepine urea analog; 1,4-Benzodiazepine-7-carboxamide, N-methyl- derivative; 74858-67-6; UNII- number to be confirmed; Contact for specific IUPAC name variants.
EINECS	Contact for details

Quality Control

Our Urea, n-(5-(2-Fluorophenyl)-2,3-Dihydro-1-Methyl-2-Oxo-1H-1,4-Benzodia Zepin-7-Yl)-N(Sup 1)-Methyl- is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements for research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.