Description

n-(5-Bromo-1,4-Dihydro-4-Oxo-6-Phenyl-2-Pyrimidinyl)-Acetamide is a specialized pyrimidine derivative, a high-purity organic intermediate of significant importance in advanced chemical synthesis. This compound matters for its role as a critical building block in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific brominated pyrimidine acetamide functionalities into their target compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting kinase inhibition or other biological pathways where the pyrimidine core is essential.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators that incorporate halogenated heterocyclic structures for enhanced efficacy.
• Organic Synthesis Building Block: Employed in academic and industrial research laboratories for constructing complex molecular architectures, leveraging its reactive bromine and amide groups for further functionalization.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials or ligands for metal-organic frameworks (MOFs), where its conjugated system can be utilized.
• Biochemical Probe Development: Can be utilized to create labeled compounds or probes for studying biological mechanisms and interactions in life science research.

Basic Information

Product Name	n-(5-Bromo-1,4-Dihydro-4-Oxo-6-Phenyl-2-Pyrimidinyl)-Acetamide
CAS No.	74856-68-1
Molecular Formula	C12H10BrN3O2
Molecular Weight	308.13 g/mol
Synonyms	5-Bromo-2-(acetylamino)-6-phenyl-4(3H)-pyrimidinone; 2-Acetamido-5-bromo-6-phenyl-4-pyrimidinone; N-(5-Bromo-4-oxo-6-phenyl-1,4-dihydro-2-pyrimidinyl)acetamide; Acetamide, N-(5-bromo-1,4-dihydro-4-oxo-6-phenyl-2-pyrimidinyl)-; 5-Bromo-6-phenyl-2-(acetylamino)pyrimidin-4(3H)-one
EINECS	Contact for details

Quality Control

Our n-(5-Bromo-1,4-Dihydro-4-Oxo-6-Phenyl-2-Pyrimidinyl)-Acetamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and scale-up applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.