Description

4-Chloro-2-(Methylthio)Pyrimidine-5-Carboxylic Acid is a high-purity pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional reactivity, offering distinct sites for nucleophilic substitution and carboxyl group transformations, which enables the construction of complex heterocyclic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of antiviral, anticancer, and other biologically active pyrimidine-based compounds.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides that utilize pyrimidine chemistry.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential intermediate for the development of specialty polymers, ligands, or organic electronic materials.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing custom fine chemicals for client projects.

Basic Information

Product Name	4-Chloro-2-(Methylthio)Pyrimidine-5-Carboxylic Acid
CAS No.	74840-34-9
Molecular Formula	C7H5ClN2O2S
Molecular Weight	218.64 g/mol
Synonyms	4-Chloro-2-(methylsulfanyl)pyrimidine-5-carboxylic acid; 2-(Methylthio)-4-chloropyrimidine-5-carboxylic Acid; 4-Chloro-2-methylthiopyrimidine-5-carboxylic Acid; 5-Pyrimidinecarboxylic acid, 4-chloro-2-(methylthio)-; 74840-34-9; 4-Chloro-2-methylmercaptopyrimidine-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(Methylthio)Pyrimidine-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.