Description

Cloricromene hydrochloride is a synthetic organic compound of significant interest in pharmaceutical research and development. This compound serves as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of advanced therapeutic agents. It is primarily sought after by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in cardiovascular and anti-inflammatory drug discovery. The material is supplied to meet the stringent purity and consistency requirements of the global life sciences industry.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel API candidates targeting platelet aggregation and thrombosis.
• Biochemical Research: Used as a reference standard or tool compound in pharmacological studies investigating vascular and inflammatory pathways.
• Preclinical Development: Serves as a key material for formulation studies, stability testing, and toxicology assessments during drug development cycles.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Analytical Standard: Utilized in quality control laboratories for method development and validation, ensuring batch-to-batch consistency.

Basic Information

Product Name	Cloricromene Hydrochloride
CAS No.	74697-28-2
Molecular Formula	C20H20ClNO5 • HCl
Molecular Weight	418.29 g/mol
Synonyms	AD6 Hydrochloride; Cloricromene HCl; 8-Monochloro-3-β-diethylaminoethyl-4-methyl-7-ethoxycarbonylmethoxycoumarin Hydrochloride; 8-Chloro-3-[2-(diethylamino)ethyl]-4-methyl-7-[(ethoxycarbonyl)methoxy]-2H-1-benzopyran-2-one Hydrochloride; AD-6; Proendotel Hydrochloride
EINECS	Contact for details

Quality Control

Our Cloricromene hydrochloride is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identity confirmation (IR, NMR) to ensure it meets exacting standards for pharmaceutical research. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.