Description

Gnrh, (Ac-Dehydro-Pro(1)-4-Cl-Phe(2)-Trp(3,6))-n-(Alpha)-Meleu(7)- is a synthetic, modified peptide analog of Gonadotropin-Releasing Hormone (GnRH). This compound is engineered for enhanced stability and specific receptor interaction, making it a critical tool in advanced endocrinology and pharmaceutical research. It is primarily utilized by research institutions and pharmaceutical developers focused on neuroendocrinology, reproductive biology, and the development of novel therapeutic agents.

Application

• Biomedical Research: As a key reagent in studies investigating the GnRH receptor pathway, signal transduction, and hormone regulation mechanisms.
• Pharmaceutical Development: Serves as a reference standard or lead compound in the R&D of novel therapeutics for hormone-dependent conditions.
• Endocrinology Studies: Used in vitro and in vivo models to understand reproductive physiology and the effects of GnRH modulation.
• Peptide Chemistry: Valuable for structure-activity relationship (SAR) studies due to its specific amino acid substitutions and modifications.
• Diagnostic Assay Development: Potential use as a calibrator or component in immunoassays and other diagnostic tests targeting the GnRH system.

Basic Information

Product Name	Gnrh, (Ac-Dehydro-Pro(1)-4-Cl-Phe(2)-Trp(3,6))-n-(Alpha)-Meleu(7)-
CAS No.	74611-71-5
Molecular Formula	C64H78ClN15O11
Molecular Weight	1260.83 g/mol
Synonyms	Ac-δ-Pro1, 4-Cl-D-Phe2, D-Trp3,6, N-α-MeLeu7-GnRH; [Ac-δ-Pro1, 4-Cl-D-Phe2, D-Trp3,6, N-α-MeLeu7]-LHRH; Modified GnRH Antagonist; GnRH Peptide Analog; Luteinizing Hormone-Releasing Hormone Analog; Gonadorelin Analog; 74611-71-5
EINECS	Contact for details

Quality Control

Our high-purity peptide products are manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity and mass spectrometry for identity confirmation, to ensure consistency and reliability for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in DMSO, Acetic Acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.