Description

3-Fluoro-5-Methylsulfonylaniline is a high-purity, functionalized aniline derivative characterized by its unique combination of fluorine and methylsulfonyl substituents. This compound serves as a versatile and critical building block in advanced organic synthesis, enabling the introduction of both electron-withdrawing groups and potential hydrogen-bond acceptors into target molecules. It is primarily utilized by pharmaceutical, agrochemical, and material science research and development teams for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and sulfonyl groups contribute to biological activity and metabolic stability.
• Material Science Precursor: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its ability to modify electronic properties and intermolecular interactions.
• Chemical Research Reagent: Serves as a versatile starting material in academic and industrial laboratories for heterocyclic chemistry, cross-coupling reactions, and the synthesis of complex molecular architectures.
• Dye and Pigment Intermediate: Facilitates the creation of specialized dyes and pigments with enhanced properties like lightfastness and color strength.

Basic Information

Product Name	3-Fluoro-5-Methylsulfonylaniline
CAS No.	74586-55-3
Molecular Formula	C7H8FNO2S
Molecular Weight	189.21 g/mol
Synonyms	5-(Methylsulfonyl)-3-fluoroaniline; 3-Fluoro-5-(methylsulfonyl)benzenamine; 3-Fluoro-5-methanesulfonylaniline; Benzenamine, 3-fluoro-5-(methylsulfonyl)-; 3-Fluoro-5-methylsulphonylaniline; 3-FA-5-MSA; 3F5MSA
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Methylsulfonylaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, GC, NMR, and FTIR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under GMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.