Description

n-Acetyl-S-(2-Cyanoethyl)-L-Cysteine is a key biochemical derivative of L-cysteine, specifically designed for advanced research and analytical applications. This compound is of significant value as a stable, characterized metabolite and reference standard in toxicological and metabolic studies. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical service providers engaged in biomarker analysis, drug metabolism and pharmacokinetics (DMPK) research, and proteomics.

Application

• Biomarker Research & Analysis: Used as a reference standard for the detection and quantification of specific mercapturic acid metabolites in biological samples, crucial for exposure and toxicology studies.
• Drug Metabolism Studies (DMPK): Serves as a stable, well-defined metabolite analog in pharmacokinetic research to understand the biotransformation pathways of parent compounds.
• Proteomics & Biochemical Research: Acts as a specialized reagent or building block in studying cysteine modifications and protein conjugation chemistry.
• Analytical Method Development: Essential for developing and validating sensitive HPLC-MS/MS or GC-MS methods in clinical and forensic toxicology laboratories.
• Reference Material Production: Supplied to manufacturers of certified reference materials (CRMs) and quality control standards for diagnostic kits and assays.

Basic Information

Product Name	n-Acetyl-S-(2-Cyanoethyl)-L-Cysteine
CAS No.	74514-75-3
Molecular Formula	C8H12N2O3S
Molecular Weight	216.26 g/mol
Synonyms	N-Acetyl-S-(2-cyanoethyl)cysteine; N-Acetyl-S-(β-cyanoethyl)-L-cysteine; N-Acetyl-3-[(2-cyanoethyl)sulfanyl]-L-alanine; L-Cysteine, N-acetyl-S-(2-cyanoethyl)-; Acetyl-S-(2-cyanoethyl)cysteine; S-(2-Cyanoethyl)-N-acetyl-L-cysteine; N-Acetyl-S-2-cyanoethylcysteine; AAMA (Acrylamide Metabolite Mercapturic Acid - related analog)
EINECS	Contact for details

Quality Control

Our n-Acetyl-S-(2-Cyanoethyl)-L-Cysteine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification (IR, NMR), and chiral purity verification to ensure identity, strength, and composition. Certificates of Analysis (COA) with detailed chromatographic data are provided and traceable to in-house reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% L-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.