Description

H-D-Phe-Pro-Arg-5-Amido-Isophthalic Acid-Dimethyl Ester Acetate Salt is a high-purity, synthetic peptide derivative designed for advanced research and development applications. This compound is valued for its role as a key intermediate or reference standard in the development of novel therapeutic agents and diagnostic tools. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on protease inhibition, cardiovascular research, and peptide chemistry.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate or building block in the synthesis of novel thrombin inhibitors and other serine protease-targeting drug candidates.
• Biochemical Assay Development: Used as a reference standard or substrate analog in the development and validation of high-throughput screening (HTS) assays for enzyme activity and inhibition studies.
• Proteomics & Peptide Chemistry: Employed as a specialized reagent in peptide synthesis and modification studies, aiding in structure-activity relationship (SAR) investigations.
• Academic Research: Utilized in university and institutional labs for fundamental research on blood coagulation pathways, hemostasis, and related physiological processes.
• Diagnostic Reagent Manufacturing: Acts as a key component in the formulation of specialized diagnostic kits and reagents for clinical testing.

Basic Information

Product Name	H-D-Phe-Pro-Arg-5-Amido-Isophthalic Acid-Dimethyl Ester Acetate Salt
CAS No.	74503-72-3
Molecular Formula	C33H43N7O8 • C2H4O2
Molecular Weight	Contact for details
Synonyms	H-D-Phe-Pro-Arg-5-Amido-IPA-DME Acetate; 5-Amidophthalic Acid-Dimethyl Ester Derivative; D-Phenylalanyl-L-prolyl-L-arginine Amide Derivative; Thrombin Inhibitor Intermediate; Ac-(D)Phe-Pro-Arg-5-Amido-IPA-DME Acetate; FPR-5-Amido-Isophthalic Acid Dimethyl Ester Acetate Salt; Peptide Inhibitor Building Block CAS 74503-72-3
EINECS	Contact for details

Quality Control

Our H-D-Phe-Pro-Arg-5-Amido-Isophthalic Acid-Dimethyl Ester Acetate Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.