Description

L-Phe-D-His-Oh is a synthetic dipeptide composed of L-phenylalanine and D-histidine. This compound is of significant interest in pharmaceutical research and development due to its role as a key intermediate or building block for more complex peptide structures. It is primarily utilized by research institutions and manufacturers in the life sciences sector for applications in drug discovery, peptide synthesis, and biochemical studies.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel therapeutic peptides and peptidomimetics.
• Biochemical Research: Used as a standard or reagent in enzymatic studies, receptor binding assays, and metabolic pathway investigations.
• Peptide Library Synthesis: A key component in combinatorial chemistry for creating diverse peptide libraries for high-throughput screening.
• Proteomics & Diagnostics: Can be employed in the development of diagnostic assays and as a tool compound in proteomic research.
• Academic Research: Utilized in university and institutional labs for studying peptide structure-activity relationships and chiral chemistry.

Basic Information

Product Name	L-Phe-D-His-Oh
CAS No.	74479-01-9
Molecular Formula	C15H20N4O3
Molecular Weight	304.35 g/mol
Synonyms	L-Phenylalanyl-D-histidine; D-His-L-Phe-OH; H-D-His-L-Phe-OH; Phe-His; Phenylalanine-Histidine dipeptide; (2S)-2-[[(2R)-2-amino-3-(1H-imidazol-4-yl)propanoyl]amino]-3-phenylpropanoic acid; FK-888 intermediate (related); Peptide building block 74479-01-9
EINECS	Contact for details

Quality Control

Our L-Phe-D-His-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.