Description

2-Phenyl-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one is a heterocyclic organic compound belonging to the fused pyrimidine class, serving as a versatile and high-value synthetic intermediate. Its core value lies in its complex bicyclic structure, which provides a critical scaffold for the development of novel bioactive molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of potential therapeutic agents targeting neurological and inflammatory pathways.

Application

• Pharmaceutical Intermediate: Key building block in the research and development of new drug candidates, especially for central nervous system (CNS) and anti-inflammatory applications.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Synthesis: Serves as a precursor for the synthesis of more complex fused heterocyclic systems with potential biological activity.
• Biochemical Tool Compound: Potential use in biochemical assays to study enzyme inhibition or receptor binding mechanisms in early-stage research.
• Academic Research: Employed in universities and research institutes for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	2-Phenyl-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one
CAS No.	74411-91-9
Molecular Formula	C₁₅H₁₄N₂O
Molecular Weight	238.29 g/mol
Synonyms	2-Phenyl-4H,6H,7H,8H,9H-pyrimido[1,2-a]pyrimidin-4-one; 2-Phenyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidine; 74411-91-9; Pyrimido[1,2-a]pyrimidin-4-one, 2-phenyl-6,7,8,9-tetrahydro-; 2-Phenyl-6,7,8,9-tetrahydro-pyrimido[1,2-a]pyrimidin-4-one
EINECS	Contact for details

Quality Control

Our 2-Phenyl-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure product stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.