Description

Arg-B-Endorphin Human CAS NO 74349-57-8 is a synthetic peptide fragment of the endogenous opioid peptide β-Endorphin, specifically corresponding to the C-terminal region. This high-purity reference standard is critical for advanced biochemical research and pharmaceutical development, enabling precise study of opioid receptor interactions and neuropeptide pathways. It is primarily utilized by research institutions, diagnostic manufacturers, and biopharmaceutical companies engaged in neuroscience, pain management research, and assay development.

Application

• Biochemical Research: Used as a high-purity reference standard in studies investigating the structure, function, and metabolism of β-Endorphin and related neuropeptides.
• Neuroscience & Pharmacology: Essential for in vitro and ex vivo assays to study opioid receptor binding affinity, selectivity, and signal transduction mechanisms.
• Diagnostic Development: Serves as a critical antigen or calibrator in the development and validation of immunoassays (e.g., ELISA, RIA) for measuring endorphin levels.
• Pharmaceutical R&D: Employed in drug discovery programs targeting the opioid system for pain relief, addiction treatment, and mood disorder therapies.
• Academic Research: A key tool for university and institutional labs exploring stress response, analgesia, and behavioral neuroendocrinology.
• Quality Control: Used as a system suitability standard in analytical laboratories to ensure the performance of chromatographic (HPLC, LC-MS) and spectroscopic methods.

Basic Information

Item	Detail
Product Name	Arg-B-Endorphin Human
CAS No.	74349-57-8
Molecular Formula	C158H251N47O46S
Molecular Weight	3466.0 g/mol (approximate)
Synonyms	β-Endorphin (22-31), human; Arg-β-Endorphin; β-Lipotropin (61-69); H-Arg-Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-OH; L-Arginine-β-endorphin; βh-Endorphin (22-31); β-Endorphin fragment 22-31; β-EP (22-31)
EINECS	Contact for details

Quality Control

Every batch of Arg-B-Endorphin Human is manufactured and analyzed under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure identity, purity, and consistency meet the exacting standards required for research and development. Certificates of Analysis (COA) detailing purity (by HPLC), peptide content, and analytical data are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. For long-term storage, desiccate at -20°C. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.