Description

H-Ala-Ala-Tyr-Ala-Ala-Oh is a synthetic pentapeptide sequence featuring a central tyrosine residue. This compound is a valuable biochemical tool and a key intermediate in peptide research and development. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for applications such as enzyme substrate studies, structure-activity relationship (SAR) investigations, and as a building block for more complex peptides.

Application

• Biochemical Research: Used as a specific substrate for studying the activity and kinetics of proteolytic enzymes like chymotrypsin and other serine proteases.
• Pharmaceutical Development: Serves as a critical intermediate or a model compound in the synthesis and design of novel therapeutic peptides.
• Structure-Activity Relationship (SAR) Studies: The defined sequence allows for the investigation of how specific amino acid residues, particularly tyrosine, influence peptide conformation and biological activity.
• Peptide Library Construction: Acts as a core structure or a component in the generation of combinatorial peptide libraries for drug discovery screening.
• Enzyme Characterization: Employed in assays to characterize enzyme specificity, inhibition, and catalytic mechanisms in academic and industrial R&D settings.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for peptide identification and quantification via HPLC or MS.

Basic Information

Product Name	H-Ala-Ala-Tyr-Ala-Ala-Oh
CAS No.	74261-52-2
Molecular Formula	C23H34N5O7
Molecular Weight	492.55 g/mol
Synonyms	Ala-Ala-Tyr-Ala-Ala; AAYAA; H-Ala-Ala-Tyr-Ala-Ala-OH; Pentapeptide AAYAA; L-Alanyl-L-alanyl-L-tyrosyl-L-alanyl-L-alanine; Ala-Ala-Tyr-Ala-Ala-OH; AAYAA Peptide; N-(L-Alanyl)-L-alanyl-L-tyrosyl-L-alanyl-L-alanine
EINECS	Contact for details

Quality Control

Our H-Ala-Ala-Tyr-Ala-Ala-Oh is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, MS, and NMR. A Certificate of Analysis (COA) detailing purity, identity, and specific test results is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.