Description

Cyclo(Methyltyrosyl-Isoleucyl-Pipecolyl-Leucyl) CAS NO 74245-26-4 is a synthetic cyclic tetrapeptide of significant interest in advanced pharmaceutical research and development. This compound serves as a crucial building block and a model structure for studying peptide conformation, receptor binding, and biological activity modulation. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel therapeutic agents, particularly in oncology and metabolic disease research. The precise cyclic structure offers enhanced metabolic stability and unique pharmacological properties compared to linear analogs.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor or scaffold in the development of novel peptide-based therapeutics.
• Biochemical Research: Used as a reference standard or probe in studies of enzyme inhibition, receptor-ligand interactions, and signal transduction pathways.
• Drug Discovery: Acts as a core structure for medicinal chemistry optimization programs aimed at improving potency, selectivity, and pharmacokinetic profiles.
• Academic Research: Employed in universities and research institutes for fundamental studies on peptide cyclization techniques and structure-activity relationships (SAR).
• Peptide Library Synthesis: Used in the generation of focused combinatorial libraries for high-throughput screening against biological targets.

Basic Information

Product Name	Cyclo(Methyltyrosyl-Isoleucyl-Pipecolyl-Leucyl)
CAS No.	74245-26-4
Molecular Formula	C33H51N5O6
Molecular Weight	613.79 g/mol
Synonyms	Cyclo(MeTyr-Ile-Pip-Leu); Cyclo(L-Methyltyrosyl-L-Isoleucyl-L-Pipecolyl-L-Leucyl); Cyclic Tetrapeptide 74245-26-4; c(MeTyr-Ile-Pip-Leu); c[Methyltyrosyl-Isoleucyl-Pipecolyl-Leucyl]; Cyclo(Methyltyrosylisoleucylpipecolylleucyl); L-Leucine, L-methyltyrosyl-L-isoleucyl-2-piperidinecarbonyl-, cyclic (1→4)-lactam; 4,7,10,13-Tetraazacyclotetradecane-1,4,7,10,13-pentaone derivative
EINECS	Contact for details

Quality Control

Our Cyclo(Methyltyrosyl-Isoleucyl-Pipecolyl-Leucyl) is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided to guarantee product integrity and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.