Description

β-Endorphin (18-31) (Human) is a specific, bioactive fragment of the human β-endorphin peptide, identified by CAS NO 74216-35-6. This compound is a critical research tool for studying opioid receptor interactions, pain modulation pathways, and neuroendocrine functions. It is primarily utilized by pharmaceutical R&D teams, academic neuroscientists, and biochemical suppliers focused on neuroscience and peptide hormone research.

Application

• Neuroscience Research: Investigation of endogenous opioid systems, receptor binding assays, and signal transduction studies.
• Pain Mechanism Studies: Used as a reference standard in models of analgesia and pain perception.
• Biochemical Standard: Serves as a high-purity calibrant in analytical methods such as HPLC and mass spectrometry for peptide quantification.
• Drug Discovery: A key intermediate or reference compound in the development of novel analgesics and central nervous system (CNS) targeting therapeutics.
• Cell Biology: Study of peptide effects on cellular processes and immune modulation in vitro.

Basic Information

Product Name	β-Endorphin (18-31) (Human)
CAS No.	74216-35-6
Molecular Formula	C70H111N19O19S
Molecular Weight	1522.8 g/mol
Synonyms	β-Endorphin (18-31), human; β-Endorphin Fragment 18-31; H-Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-OH; β-Lipotropin (61-76); LPH (61-76); Corticotropin-like intermediate lobe peptide (CLIP) related peptide; Opioid peptide fragment; [Met5]-Enkephalin related peptide
EINECS	Contact for details

Quality Control

Our β-Endorphin (18-31) (Human) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.