Description

Hydroxygentamicin CAS NO 74191-35-8 is a semi-synthetic aminoglycoside antibiotic derived from gentamicin. This compound is valued for its enhanced spectrum of activity and potential for improved therapeutic profiles compared to its parent molecule. It is primarily utilized in pharmaceutical research and development for creating advanced antibacterial agents. The product is essential for manufacturers and R&D facilities focused on next-generation anti-infective therapies.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of novel aminoglycoside antibiotics.
• Antibacterial Research: Used in microbiological and pharmacological studies to investigate structure-activity relationships.
• Veterinary Medicine Development: Employed in the formulation of advanced treatments for bacterial infections in animals.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical labs.
• Biochemical Research: Utilized in studies exploring bacterial protein synthesis inhibition mechanisms.

Basic Information

Product Name	Hydroxygentamicin
CAS No.	74191-35-8
Molecular Formula	C21H43N5O7 (Gentamicin C1 base formula - representative)
Molecular Weight	477.60 g/mol (Gentamicin C1 base)
Synonyms	Hydroxygentamicin; 2-Deoxystreptamine derivative; 3''/4''-Dideoxy-6'-C-methylneamine; Gentamicin C1, 6'-C-methyl-; Antibiotic G 418 related compound; 6'-C-Methylgentamicin C1; (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-Diamino-3-[[(2R,3R,6S)-3-amino-6-(aminomethyl)oxan-2-yl]oxy]-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol
EINECS	Contact for details

Quality Control

Our Hydroxygentamicin is manufactured under strict quality systems. Each batch is tested to ensure high purity and consistency, with specifications aligned with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.