Description

N(1),N(8)-Bis(γ-Glutamyl)Spermidine is a specialized polyamine derivative where spermidine is conjugated with two γ-glutamyl residues. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a potential metabolic intermediate and its involvement in cellular processes related to polyamine metabolism. It serves as a critical reference standard and building block for researchers in life sciences, particularly those investigating enzymology, metabolic pathways, and novel therapeutic agents. The product is supplied as a high-purity material to ensure reliable and reproducible experimental results.

Application

• Biochemical Research: Used as a key substrate or inhibitor in enzymatic studies, particularly for enzymes involved in polyamine and glutamyl transfer reactions.
• Pharmaceutical R&D: Serves as a reference compound or synthetic intermediate in the development of drugs targeting cellular growth, proliferation, and related disorders.
• Metabolomics & Pathway Analysis: Employed as an analytical standard for the identification and quantification of this metabolite in complex biological samples.
• Life Science Reagents: Incorporated into specialized assay kits and diagnostic tools for studying polyamine metabolism and its physiological implications.
• Academic Research: Utilized in university and institutional labs for fundamental studies in biochemistry, cell biology, and molecular biology.

Basic Information

Product Name	N(1),N(8)-Bis(γ-Glutamyl)Spermidine
CAS No.	74141-51-8
Molecular Formula	C22H39N7O8
Molecular Weight	529.59 g/mol
Synonyms	N1,N8-Bis(γ-Glutamyl)spermidine; γ-Glutamylspermidine (bis form); Bis(γ-glutamyl)spermidine; N1,N8-Di(γ-glutamyl)spermidine; Spermidine, N1,N8-bis(γ-glutamyl)-; N1,N8-Bis-(5-L-glutamyl)spermidine; (S)-2-Amino-5-[[(4-[[(S)-1,5-diaminopentyl]amino]butyl)amino]-5-oxopentanoyl]amino]pentanedioic acid
EINECS	Contact for details

Quality Control

Our N(1),N(8)-Bis(γ-Glutamyl)Spermidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.