Description

N(1)-(γ-Glutamyl)Spermine is a specialized polyamine derivative formed by the conjugation of glutamic acid and spermine. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a potential intermediate or modulator in polyamine metabolism pathways. It is primarily utilized by research institutions and biotechnology companies focused on cell biology, oncology, and metabolic studies. The product is supplied with a high level of purity to meet the stringent demands of advanced scientific investigation.

Application

• Biochemical Research: Used as a reference standard or substrate in enzymatic studies related to polyamine biosynthesis and catabolism.
• Pharmaceutical Development: Investigated for its potential biological activity and role as a precursor or metabolite in drug discovery programs, particularly in oncology.
• Cell Culture & Physiology: Employed in studies exploring the effects of polyamine analogs on cell growth, differentiation, and apoptosis.
• Metabolic Pathway Analysis: Serves as a key intermediate for tracing and understanding complex polyamine metabolic networks in various organisms.
• Enzyme Inhibition Studies: Utilized to study the mechanism and kinetics of enzymes like transglutaminases or polyamine oxidases.
• Diagnostic Reagent Manufacturing: Can be used in the development of diagnostic kits and assays for research purposes.

Basic Information

Product Name	N(1)-(γ-Glutamyl)Spermine
CAS No.	74141-49-4
Molecular Formula	C19H39N7O4
Molecular Weight	429.56 g/mol
Synonyms	γ-Glutamylspermine; N1-(γ-Glutamyl)spermine; Glutamylspermine; (S)-2-Amino-5-[[(4-[[4-(3-aminopropylamino)butyl]amino)butyl]amino)pentanedioic acid; N1-γ-Glutamylspermine; Polyamine derivative 74141-49-4; N1-(γ-L-Glutamyl)spermine
EINECS	Contact for details

Quality Control

Our N(1)-(γ-Glutamyl)Spermine is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation. We adhere to stringent in-house quality standards suitable for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.