Description

4-Isothiocyanatophenyl-6-Phospho α-D-Mannopyranoside is a specialized glycosyl phosphate derivative functionalized with an isothiocyanate group. This compound matters as a critical intermediate for the synthesis of glycoconjugates and affinity ligands, enabling precise biochemical labeling and purification. It is primarily needed by researchers and manufacturers in the fields of glycobiology, pharmaceutical development, and diagnostic assay production, where it serves as a key building block for creating targeted probes and separation matrices.

Application

• Glycoconjugate Synthesis: Key intermediate for creating neoglycoconjugates and glycoclusters for biological studies.
• Affinity Chromatography Ligand: Used to functionalize solid supports (e.g., agarose beads) for the purification of lectins and carbohydrate-binding proteins.
• Biochemical Probe Development: Serves as a precursor for fluorescent or biotinylated probes to study carbohydrate-protein interactions.
• Pharmaceutical Research: Employed in the design and development of carbohydrate-based drug candidates and vaccines.
• Diagnostic Reagents: Utilized in the manufacture of components for diagnostic kits targeting specific sugar-binding events.
• Enzyme Substrate Analogue: Acts as an inhibitor or substrate analogue for glycosyltransferases and related enzymes.

Basic Information

Product Name	4-Isothiocyanatophenyl-6-Phospho α-D-Mannopyranoside
CAS No.	74141-15-4
Molecular Formula	C13H16NO10PS
Molecular Weight	409.31 g/mol
Synonyms	p-Isothiocyanatophenyl 6-O-Phosphono-α-D-mannopyranoside; 4-Isothiocyanatophenyl α-D-Mannopyranoside 6-Phosphate; PITC-Phenyl Mannoside 6-Phosphate; 6-Phospho-α-D-mannopyranosylphenyl isothiocyanate; α-D-Mannopyranoside, 4-isothiocyanatophenyl 6-(dihydrogen phosphate); Glycosyl phosphate isothiocyanate derivative
EINECS	Contact for details

Quality Control

Our 4-Isothiocyanatophenyl-6-Phospho α-D-Mannopyranoside is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.