Description

N(2)-Dansyl-L-Arginine-4-T-Butylpiperidine Amide is a specialized, high-purity synthetic peptide derivative featuring a dansyl fluorophore. This compound is primarily valued as a critical biochemical tool and research reagent for studying enzyme kinetics and protein interactions. It is essential for researchers and manufacturers in pharmaceutical R&D, proteomics, and diagnostic assay development, particularly in the investigation of serine protease mechanisms.

Application

• Biochemical Research: As a fluorogenic or chromogenic substrate for studying the activity and inhibition of trypsin-like serine proteases.
• Pharmaceutical Development: Used in high-throughput screening (HTS) assays to identify and characterize novel protease inhibitors for therapeutic applications.
• Diagnostic Reagents: A key component in the formulation of enzymatic assay kits for clinical and research laboratories.
• Proteomics & Enzymology: Employed in mechanistic studies to understand substrate specificity and catalytic pathways of arginine-specific enzymes.
• Quality Control: Serves as a reference standard for the calibration and validation of analytical methods in biopharmaceutical manufacturing.

Basic Information

Product Name	N(2)-Dansyl-L-Arginine-4-T-Butylpiperidine Amide
CAS No.	74133-53-2
Molecular Formula	C27H45N7O3S
Molecular Weight	547.76 g/mol
Synonyms	Dansyl-L-Arginine-4-Tert-Butylpiperidine Amide; DAPA; N2-Dansyl-L-arginine 4-tert-butylpiperidine amide; N2-(5-Dimethylaminonaphthalene-1-sulfonyl)-L-arginine 4-tert-butylpiperidine amide; BOC-DAPA; Protease Substrate DAPA; Trypsin Substrate DAPA; Fluorogenic Arginine Substrate
EINECS	Contact for details

Quality Control

Our N(2)-Dansyl-L-Arginine-4-T-Butylpiperidine Amide is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and NMR for structural verification, to ensure it meets the stringent requirements for research and diagnostic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.