Description

2,4(1H,3H)Pyrimidinedione, 3-[[(5-Chloro-3-Methylsalicyl)Methylamino]M Ethyl]- is a specialized pyrimidinedione derivative with a complex salicylamide-based side chain, representing a high-value intermediate in advanced organic synthesis. This compound is critical for research and development in the pharmaceutical sector, where its unique structure serves as a key building block for novel active pharmaceutical ingredients (APIs). It is primarily sought after by fine chemical manufacturers, contract research organizations (CROs), and academic research institutions focused on medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly in therapeutic areas targeting specific enzymatic pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Biochemical Reagent: May be employed in biochemical assays as a potential inhibitor or modulator for studying enzyme function and signal transduction.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis for creating complex, high-value molecules with specific functional group arrangements.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	2,4(1H,3H)Pyrimidinedione, 3-[[(5-Chloro-3-Methylsalicyl)Methylamino]M Ethyl]-
CAS No.	74051-49-3
Molecular Formula	C15H16ClN3O3
Molecular Weight	321.76 g/mol
Synonyms	3-[[(5-Chloro-3-methylsalicyl)methylamino]methyl]-2,4(1H,3H)-pyrimidinedione; 3-[(5-Chloro-3-methyl-2-hydroxybenzyl)(methyl)aminomethyl]-1H-pyrimidine-2,4-dione; 5-Chloro-3-methyl-N-methyl-N-[(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-3-yl)methyl]salicylamide; Uracil derivative 74051-49-3; 3-[(N-Methyl-N-(5-chloro-3-methylsalicyl)amino)methyl]uracil
EINECS	Contact for details

Quality Control

Our production of this high-purity intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and mass spectrometry to ensure structural identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with each shipment. We support development and commercial projects, with capabilities to meet research-grade through to cGMP standards based on customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.