Description

3-Deacetylvecuronium is a key intermediate in the synthesis of the neuromuscular blocking agent, Vecuronium Bromide. This compound is of critical importance in the pharmaceutical supply chain for the production of high-purity active pharmaceutical ingredients (APIs). It is primarily required by pharmaceutical manufacturers, research institutions, and fine chemical suppliers engaged in the development and production of anesthetic and muscle relaxant formulations.

Application

• Pharmaceutical Intermediate: Primary use as a critical synthetic precursor in the commercial production of Vecuronium Bromide, a non-depolarizing neuromuscular blocking agent.
• API Synthesis: Integral component in multi-step organic synthesis for the manufacture of high-purity Active Pharmaceutical Ingredients (APIs) in the anesthetic class.
• Research & Development: Used in pharmacological and medicinal chemistry research for developing new analogs or studying structure-activity relationships of neuromuscular blockers.
• Reference Standard: Serves as a chromatographic reference standard (CRS) or impurity standard in quality control laboratories for analytical method development and validation.
• Fine Chemical Production: Employed by fine chemical and custom synthesis organizations for contract manufacturing and scale-up projects.

Basic Information

Product Name	3-Deacetylvecuronium
CAS No.	74041-85-3
Molecular Formula	C33H53N2O3+
Molecular Weight	525.79 g/mol
Synonyms	Vecuronium Impurity F; 3-Desacetylvecuronium; 1-[(2β,3α,5α,16β,17β)-3,17-Bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium; Pancuronium, 3'-desacetyl-; Norcuron Impurity F; 3'-Desacetylvecuronium; 3-Desacetyl Vecuronium
EINECS	Contact for details

Quality Control

Our 3-Deacetylvecuronium is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets stringent specifications for pharmaceutical intermediates. Certificates of Analysis (COA) are provided with each shipment, detailing batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.