Description

6-(2,2,2-Trifluoroethoxy)-1H-Purine is a specialized purine derivative, a key building block in advanced organic synthesis and pharmaceutical research. Its core value lies in the introduction of a trifluoroethoxy moiety, which can significantly alter the physicochemical and metabolic properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical, agrochemical, and life science industries for the development of novel active ingredients and biochemical probes.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of nucleoside analogs and other potential therapeutic agents targeting viral infections or cancer.
• Agrochemical Research: Used in the development of novel herbicides or plant growth regulators, where the fluorine-containing group can enhance bioavailability and stability.
• Biochemical Probe Synthesis: Serves as a scaffold for creating labeled compounds or inhibitors used in enzymatic studies and mechanism-of-action research.
• Organic Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies to optimize drug candidate properties like potency and selectivity.
• Material Science Research: Potential use in the synthesis of specialized organic materials or ligands for catalytic systems.

Basic Information

Product Name	6-(2,2,2-Trifluoroethoxy)-1H-Purine
CAS No.	73972-56-2
Molecular Formula	C7H5F3N4O
Molecular Weight	218.14 g/mol
Synonyms	6-(2,2,2-Trifluoroethoxy)-9H-purine; 6-(Trifluoroethoxy)purine; 1H-Purine, 6-(2,2,2-trifluoroethoxy)-; 9H-Purine, 6-(2,2,2-trifluoroethoxy)-; 6-O-(2,2,2-Trifluoroethyl)purine; Purine, 6-(2,2,2-trifluoroethoxy)-; 6-Trifluoroethoxypurine
EINECS	Contact for details

Quality Control

Our 6-(2,2,2-Trifluoroethoxy)-1H-Purine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.