Description

7-Chloro-L-Tryptophan is a halogenated derivative of the essential amino acid L-tryptophan, featuring a chlorine atom at the 7-position of the indole ring. This specific modification makes it a valuable chiral building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, particularly those targeting neurological and psychiatric disorders.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and metabolic pathway research due to its structural similarity to natural tryptophan.
• Peptide Synthesis: Incorporated into custom peptides to study structure-activity relationships (SAR) and to create peptides with modified biological properties.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Proteomics & Labeling: Potential use in the development of chemical probes and affinity tags for protein labeling and proteomic analysis.
• Agrochemical Research: Investigated as an intermediate in the development of new plant growth regulators or specialized agrochemicals.

Basic Information

Product Name	7-Chloro-L-Tryptophan
CAS No.	73945-46-7
Molecular Formula	C11H11ClN2O2
Molecular Weight	238.67 g/mol
Synonyms	(S)-2-Amino-3-(7-chloro-1H-indol-3-yl)propanoic acid; L-7-Chlorotryptophan; 7-Chlorotryptophan; 7-Cl-Trp; 7-Chloro-L-tryptophan; 7-Chloro-L-Trp; 7-Chloro-L-α-amino-1H-indole-3-propanoic acid; 7-Chloro-L-α-aminohydrocinnamic acid (indole derivative)
EINECS	Contact for details

Quality Control

Our 7-Chloro-L-Tryptophan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.