Description

Dl-Threo-Dihydrosphingosine is a synthetic, racemic diastereomer of the fundamental sphingolipid backbone, dihydrosphingosine. This compound serves as a critical precursor and biochemical tool for research into sphingolipid metabolism, cell signaling, and membrane biology. It is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and life science research sectors who require high-purity intermediates for synthesizing complex lipids or studying cellular processes.

Application

• Biochemical Research: A key intermediate in the study of sphingolipid metabolism, ceramide synthesis, and associated cell signaling pathways (e.g., apoptosis, proliferation).
• Pharmaceutical Intermediate: Used in the synthesis of more complex sphingolipid analogs and potential therapeutic agents targeting lipid-mediated diseases.
• Lipidomics Standard: Serves as a critical reference standard in mass spectrometry-based lipidomic analysis for accurate identification and quantification.
• Cell Biology Studies: Employed to investigate the role of sphingolipids in cell membrane structure, fluidity, and the function of lipid rafts.
• Enzyme Substrate/Inhibitor Studies: Utilized as a substrate for enzymes like serine palmitoyltransferase or dihydroceramide desaturase in mechanistic and kinetic studies.
• Cosmeceutical Research: Explored for its potential role in skin barrier function and as a precursor for bioactive lipids in advanced skincare formulations.

Basic Information

Item	Details
Product Name	Dl-Threo-Dihydrosphingosine
CAS No.	73938-69-9
Molecular Formula	C18H39NO2
Molecular Weight	301.51 g/mol
Synonyms	(2S,3R)-2-Amino-1,3-octadecanediol (Threo isomer); D-erythro-Dihydrosphingosine (racemic threo form); (±)-Threo-Dihydrosphingosine; Dihydro-D-erythro-sphingosine (racemic); Sphinganine (racemic threo isomer); 2-Amino-1,3-octadecanediol (DL-threo-); DL-threo-2-Amino-1,3-octadecanediol; 4-Dihydroxysphinganine
EINECS	Contact for details

Quality Control

Our Dl-Threo-Dihydrosphingosine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for isomeric composition, and identity confirmation by IR and MS. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. Due to its hygroscopic nature, the container should be kept in a dry environment and allowed to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isomeric Purity (Chiral HPLC)	DL-Threo ≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.