Description

H-D-Leu-Oet Hcl is a high-purity, protected amino acid derivative essential for advanced peptide synthesis. This compound serves as a critical chiral building block, enabling the precise construction of complex peptides and peptidomimetics with defined stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, process development, and the production of active pharmaceutical ingredients (APIs).

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key intermediate for incorporating the D-leucine residue into peptide chains under standard coupling conditions.
• Solution-Phase Peptide Synthesis: Used in the synthesis of longer or complex peptides where solution-phase methodologies are preferred.
• Pharmaceutical Research: A vital raw material in the discovery and development of novel therapeutic peptides targeting various diseases.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for peptide-based Active Pharmaceutical Ingredients (APIs).
• Biochemical Research: Used to study enzyme-substrate interactions, receptor binding, and the structure-activity relationships (SAR) of peptides.
• Production of Custom Peptides: A fundamental component for contract research organizations (CROs) and manufacturers producing bespoke peptides for clients.

Basic Information

Product Name	H-D-Leu-Oet Hcl
CAS No.	73913-65-2
Molecular Formula	C8H18ClNO2
Molecular Weight	195.69 g/mol
Synonyms	D-Leucine ethyl ester hydrochloride; Ethyl D-leucinate hydrochloride; (R)-2-Amino-4-methylpentanoic acid ethyl ester hydrochloride; H-D-Leu-OEt·HCl; D-Leu-OEt·HCl; D-Leucine ethyl ester HCl; D-Leu-OEt hydrochloride; UNII-2Y8K8Q0F8F
EINECS	Contact for details

Quality Control

Our H-D-Leu-Oet Hcl is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical and research applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Specific Rotation	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.