Description

o-Phospho-D-Serine is a phosphorylated derivative of the D-isomer of the amino acid serine, serving as a crucial biochemical building block and research reagent. This compound is particularly valuable for its role in studying chiral specificity in phosphorylation pathways and protein interactions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in peptide synthesis, enzyme studies, and as a reference standard.

Application

• Biochemical Research: As a chiral substrate for studying kinase and phosphatase enzyme specificity and activity.
• Pharmaceutical Intermediates: Used in the synthesis of specialized peptides and potential therapeutic agents targeting phosphorylation-dependent processes.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in HPLC and LC-MS.
• Cell Culture & Neuroscience Studies: Investigated for its potential effects on cellular signaling pathways and neuronal function.
• Enzyme Inhibitor Development: A key compound for screening and developing inhibitors of phosphoserine-binding proteins or domains.

Basic Information

Product Name	o-Phospho-D-Serine
CAS No.	73913-63-0
Molecular Formula	C3H8NO6P
Molecular Weight	185.07 g/mol
Synonyms	D-Phosphoserine; (R)-2-Amino-3-phosphonopropanoic acid; D-O-Phosphoserine; D-Serine O-phosphate; (2R)-2-Amino-3-(phosphonooxy)propanoic acid; Phospho-D-serine; D-Serine phosphate
EINECS	Contact for details

Quality Control

Our o-Phospho-D-Serine is produced under a rigorous quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (D-isomer)
Water Content (KF)	≤ 2.0%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.