Description

Acth, 2-Nitro-5-Azidophenylsulfenyl- CAS NO 73905-69-8 is a specialized chemical reagent featuring a sulfenyl group and a photoreactive azido moiety. This compound is valued for its role as a cross-linking agent and a photoaffinity label in advanced biochemical and proteomic research. It is primarily utilized by research institutions and pharmaceutical developers engaged in protein structure analysis, enzyme mechanism studies, and the development of novel bioconjugation techniques.

Application

• Photoaffinity Labeling: A critical tool for identifying and mapping protein-ligand binding sites and studying transient molecular interactions.
• Bioconjugation & Cross-linking: Used to create covalent bonds between biomolecules under controlled light activation for constructing stable complexes.
• Proteomics Research: Employed in activity-based protein profiling (ABPP) to tag and isolate active enzymes within complex biological samples.
• Chemical Biology Probes: Serves as a key building block for synthesizing probes that investigate enzyme function and metabolic pathways.
• Material Surface Modification: Applied in modifying surfaces with bioactive molecules for biosensor and diagnostic device development.
• Pharmaceutical R&D: Facilitates the study of drug-target interactions and aids in the early-stage development of therapeutic agents.

Basic Information

Product Name	Acth, 2-Nitro-5-Azidophenylsulfenyl- CAS NO 73905-69-8
CAS No.	73905-69-8
Molecular Formula	C14H9N5O2S2
Molecular Weight	343.38 g/mol
Synonyms	2-Nitro-5-azidophenylsulfenyl chloride; 5-Azido-2-nitrophenylsulfenyl chloride; ANP-SCl; 1-Azido-4-[(chlorosulfanyl)methyl]-2-nitrobenzene; 2-Nitro-5-azidobenzenesulfenyl chloride; Photoactivatable crosslinker; Sulfenylating reagent; ACTH derivative
EINECS	Contact for details

Quality Control

Our Acth, 2-Nitro-5-Azidophenylsulfenyl- is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label. Due to its hygroscopic and light-sensitive nature, the container should be allowed to reach room temperature before opening to minimize moisture uptake, and handling should be performed under subdued light conditions.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in common organic solvents (DMSO, DMF, Acetonitrile)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.